Podcast Maker is a tool for Mac OS X that makes podcasting simple. Novices can become podcasters and professionals can podcast with much less effort and time.
Create your content the way you usually do: with GarageBand, Audio Hijack Pro, QuickTime Pro, etc. Then drag in your content into Podcast Maker. You can drag files directly in from iTunes and iPhoto. You can even import files that are already out on the web. As long as it is a podcast friendly format (mp3, m4a, mov, mp4, m4v, pdf) Podcast Maker will podcast it.
30 day free trial, requires:

• Mac OS X 10.4 or higher
• QuickTime 7.0.2 or higher