aMule: The all-platform Mule.
aMule is an eMule-like client for the eD2k and Kademlia networks
Currently aMule (officially) supports a wide variety of platforms and operating systems, being compatible with more than 60 different hardware+OS configurations.
aMule is entirely free, it’s sourcecode is released under the GPL just like eMule, and includes no adware or spyware as is often found in proprietary P2P applications.
aMule has most features of the eMule client and is currently availabe in 28 languages.
This particular download runs on both the new Intel Macs as well as on PowerPC based ones. Requires OS X 10.4 (Tiger).