Although lots of programs available for UNIX and UNIX-derived systems, such as Linux, Solaris and FreeBSD, certain individual applications are available only under Windows. With Wine, you can run most Windows applications under UNIX. Wine is not an emulator in the true sense, but rather implements the APIs of Windows under X-Windows. Thus, almost all programs of the above systems can be integrated. Wine partially supports Direct3D, meaning you can run games. The tool also supports the X 11 desktop and RPC over HTTP.

Conclusion
Various Windows programs run with Wine on a UNIX system. Programs such as Photoshop CS2 are supported without any problems. A list on the developers’ site shows which applications are supported.